Searchable abstracts of presentations at key conferences in endocrinology

ea0029p869 | Endocrine tumours and neoplasia | ICEECE2012

Antiproliferative effect and control of catecholamine release with octreotide in a patient with giant bilateral pheochromocytoma

Katalinic D. , Plestina S. , Vrkljan M. , Aleric I. , Maric A.

Introduction: Pheochromocytomas are rare but treacherous catecholamine-producing tumors of the medulla of the adrenal glands (originating in the chromaffin cells), or extra-adrenal chromaffin tissue. We refer a case with stabilization of tumor growth and hormonal improvements following repeated s.c. injections of octreotide.Case report: We report a female patient aged 35 with a finding of bilateral adrenal mass with sever cardiovascular symptomatology (f...

ea0029p977 | Female Reproduction | ICEECE2012

Erythrocytosis and thrombocytosis secondary to hypertestosteronemia caused by ovarian leydig cell tumor

Mirosevic G. , Butorac D. , Kruljac I. , Vrkljan M.

Testosterone has a dose-dependent stimulatory effect on erythropoiesis but the mechanism is poorly understood. Although both erythroblasts and megakaryocytes express androgen receptors, testosterone’s effect on thrombopoiesis in humans has never been studied.We report a case of 53-years-old woman presented with androgenic alopecia, hirsutism, facial redness and hoarse voice. She was a non-smoker and had a history of well-controlled diabetes mellitus...

ea0026p722 | Diabetes (epidemiology, pathophysiology) | ECE2011

Impact of INSR His1085 and IRS1 Gly972Arg genetic variability on dyslipidaemia in patients with metabolic syndrome and type 2 diabetes

Katalinic D , Nikolac N , Zjacic-Rotkvic V , Solter M , Topic E , Vrkljan M , Plestina S

Introduction: The metabolic syndrome is increasingly recognized as a powerful predictor of patient risk for developing cardiovascular and cerebrovascular complications. It is viewed as the phenotypic confluence of atherogenic dyslipidaemia, hypertension, central obesity and insulin resistance (with or without type 2 diabetes) resulting from dysregulated gene expression and lifestyle behaviours.Aim: Because insulin resistance is a core defect in type 2 di...

ea0011p447 | Endocrine tumours and neoplasia | ECE2006

Pituitary tumors in republic of Croatia

Vrkljan M , Maric A , Matovinovic M , Cerina V , Herman D , Pecina HI

Over the 10 percentage of all intracranial tumors are pituitary tumors.Their malignicity depends on their localisation, meanwhile their biological nature is benign. Regarding the size there are microadenomas (smaller than 10 milimeters) and macroadenomas (10 milimeters or more).Clinical manifestations of pituitary tumors depend on their localisation and hormonal activity. They are either hormonally functional or nonfunctional, resp...

ea0029p1204 | Obesity | ICEECE2012

Different metabolic response to intagastric balloon treatment between non-morbid and morbid type of obesity

Nikolic M. , Mirosevic G. , Kruljac I. , Vrkljan M. , Supanc V. , Ljubicic N. , Duvnjak M. , Budimir I. , Pezo Nikolic B. , Sabol M. , Nikolac I. , Bekavac Beslin M.

BioEnterics Intragastric Balloon (BIB) is a non-invasive procedure which proved to be effective in short-term treatment of obesity. It’s effect on alterations in metabolic parameters is poorly understood. Since our previous study showed different ghrelin and leptin response between groups of morbidly (M) and non-morbidly (NM) patients after BIB placement, we aimed to investigate the alteration dynamics in metabolic parameters between these two groups.<p class="abstext...